AlphaProteo

DeepMind's binder design system - no code or weights released; trusted-tester access only.

Developer: Google DeepMind

UnverifiedCost unverified

Overview

Developer
Google DeepMind
Commercial rights
Unverified
Commercial cost
Cost unverified
Compute
Hosted service
Open weights
No
Last verified

Capabilities

Designs de novo protein binders to a specified target site, with reported nanomolar-to-picomolar affinities straight out of the model. Input (per the trusted-tester notebook): a target PDB ID and the target region; output: binder designs returned by DeepMind, not computed locally. There is no model you can run.

When to use it

Nothing to adopt today: include it in a landscape review, not a pipeline. BindCraft, RFdiffusion and BoltzGen are what you can actually run for binder design.

Input / Output

Input
Not documented
Output
Not documented

No structured input/output statement is recorded for this tool; see Capabilities above.

Compute

Hosted service. Other tools with this compute profile →

Commercial Licensing

Commercial rights — may a company use it?

Unverified

Licence as writtenApache License 2.0 covers only the input-preparation notebooks in the public repo; the model itself is unreleased

The only public artefact is the ap_trusted_testers repository, whose README describes a Colab that helps 'users of the AlphaProteo Trusted Tester Program' prototype requests and visualise target regions - an input builder, not the model. No weights, no inference code and no terms for commercial use of the designs are published, so rights are unverified.

We could not find a published statement that settles it (often: the model weights carry no licence). Treat as unknown.

Commercial cost — is commercial use free of charge?

Cost unverified

No price exists because no product exists. Access is by DeepMind's trusted-tester programme, whose commercial terms are not published.

Price and rights are separate: this panel is about money, the panel above is about permission.

  • Commercial OK ≠ Free of charge. A tool can be licensed for company use and still need a paid licence for a dependency (BindCraft → PyRosetta).
  • Free download ≠ Commercially licensed. Weights you can download at no cost may still forbid commercial use (AlphaFold 3).
  • Unverified ≠ Commercially permitted. If no published statement settles it, treat it as unknown — not as a yes.
  • Every component counts. Each status considers the code licence, the model-weights terms, required dependencies and any terms of use.

Model Weights

Weights not openly downloadable. A separate weights licence is Not documented as its own field; where weights carry different terms from the code, that is stated in the licence explanation above.

Dependencies

Not documented as a separate field. Any dependency that affects commercial use (for example a paid PyRosetta licence) is named in the licence and cost explanations above.

Official References

From the makers of FoldScout

From AI Design to Wet-Lab Validation

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