UniProt
Reference protein sequence and functional annotation database.
Developer: UniProt Consortium (EMBL-EBI, SIB, PIR)
Overview
- Developer
- UniProt Consortium (EMBL-EBI, SIB, PIR)
- Category
- Data and structure resources
- Commercial rights
- Commercial OK
- Commercial cost
- Free commercially
- Compute
- Hosted service
- Open weights
- Yes
- Last verified
Capabilities
Reference sequences and annotation. Input: accession, gene or text query; output: canonical sequences, isoforms, domains, PTMs and functional annotation - the identity layer for any target you design against.
When to use it
Canonical source for target sequences, isoforms, domains and PTM annotation before any design run. Annotation quality varies sharply between reviewed (Swiss-Prot) and unreviewed (TrEMBL) entries.
Input / Output
- Input
- accession, gene or text query
- Output
- canonical sequences, isoforms, domains, PTMs and functional annotation - the identity layer for any target you design against
Compute
Hosted service. Other tools with this compute profile →
Commercial Licensing
Commercial rights — may a company use it?
Commercial use OKLicence as writtenCreative Commons Attribution 4.0 International (CC BY 4.0)
The UniProt license help page states CC BY 4.0 applies to all copyrightable parts of their databases, with a disclaimer that some data may be covered by patents or other rights.
The licence read at the source allows use by a company. Attribution or copyleft conditions may still apply — read the note.
Commercial cost — is commercial use free of charge?
Free for commercial useFree under CC BY 4.0, bulk downloads included.
Price and rights are separate: this panel is about money, the panel above is about permission.
- Commercial OK ≠ Free of charge. A tool can be licensed for company use and still need a paid licence for a dependency (BindCraft → PyRosetta).
- Free download ≠ Commercially licensed. Weights you can download at no cost may still forbid commercial use (AlphaFold 3).
- Unverified ≠ Commercially permitted. If no published statement settles it, treat it as unknown — not as a yes.
- Every component counts. Each status considers the code licence, the model-weights terms, required dependencies and any terms of use.
Model Weights
Open weights. A separate weights licence is Not documented as its own field; where weights carry different terms from the code, that is stated in the licence explanation above.
Dependencies
Not documented as a separate field. Any dependency that affects commercial use (for example a paid PyRosetta licence) is named in the licence and cost explanations above.
Official References
- Official site / repo
- uniprot.org
- Licence sources
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Get told when a licence changes
Licences on these tools do change. One short email when a status flips or a tool is added. No other use of your address.