Observed Antibody Space (OAS)
Over a billion annotated antibody repertoire sequences, paired and unpaired.
Developer: OPIG, University of Oxford
Overview
- Developer
- OPIG, University of Oxford
- Category
- Data and structure resources
- Commercial rights
- Commercial OK
- Commercial cost
- Free commercially
- Compute
- Hosted service
- Open weights
- Yes
- Last verified
Capabilities
Antibody repertoire sequences. Input: a query over studies/species/chains; output: over a billion annotated BCR sequences, paired and unpaired, for training language models and checking whether a CDR looks natural.
When to use it
Use for training or benchmarking antibody language models and for germline/naturalness baselines. Study-level batch effects and uneven donor coverage mean naive frequency statistics mislead.
Input / Output
- Input
- a query over studies/species/chains
- Output
- over a billion annotated BCR sequences, paired and unpaired, for training language models and checking whether a CDR looks natural
Compute
Hosted service. Other tools with this compute profile →
Commercial Licensing
Commercial rights — may a company use it?
Commercial use OKLicence as writtenCreative Commons Attribution 4.0 International (CC BY 4.0)
The OAS homepage states: 'Please note that the data contained within OAS is available under a CC-BY 4.0 license.'
The licence read at the source allows use by a company. Attribution or copyleft conditions may still apply — read the note.
Commercial cost — is commercial use free of charge?
Free for commercial useFree under CC BY 4.0, including for commercial training runs; attribute OAS and the underlying studies.
Price and rights are separate: this panel is about money, the panel above is about permission.
- Commercial OK ≠ Free of charge. A tool can be licensed for company use and still need a paid licence for a dependency (BindCraft → PyRosetta).
- Free download ≠ Commercially licensed. Weights you can download at no cost may still forbid commercial use (AlphaFold 3).
- Unverified ≠ Commercially permitted. If no published statement settles it, treat it as unknown — not as a yes.
- Every component counts. Each status considers the code licence, the model-weights terms, required dependencies and any terms of use.
Model Weights
Open weights. A separate weights licence is Not documented as its own field; where weights carry different terms from the code, that is stated in the licence explanation above.
Dependencies
Not documented as a separate field. Any dependency that affects commercial use (for example a paid PyRosetta licence) is named in the licence and cost explanations above.
Official References
- Official site / repo
- opig.stats.ox.ac.uk/webapps/oas
- Licence sources
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