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InstructPro2

Natural-language-guided protein design with antibody CDR and ligand-binding applications (research release).

Developer: InstructPro2 research authors (chovak GitHub)

Unverified
COMMERCIAL RIGHTSUnverified
COMMERCIAL FEEUnverified
COMPUTESingle Gpu
MODEL WEIGHTSAvailable

Overview

Developer
InstructPro2 research authors (chovak GitHub)
Category
antibody-specific design
Commercial rights
Unverified
License fee
Unverified
Open weights
Yes
Last verified
2026-10-17
Added to FoldScout
2026-10-17

Capabilities

Research model for natural-language-conditioned protein sequence design, including antibody CDR and ligand-binding tasks. Reported benchmark results are author-reported and not independently reproduced; no experimental performance ranking is implied.

When to use it

Explore research workflows for language-guided protein, antibody CDR and ligand-binding design; validate outputs independently and review complete commercial rights before paid use.

Compute

Compute classification: single-gpu. This is a planning estimate, not a throughput benchmark; check the linked model installation documents for exact requirements.

Example use cases

  • Explore research workflows for language-guided protein, antibody CDR and ligand-binding design; validate outputs independently and review complete commercial rights before paid use.

Workflow summary from this model’s existing source-referenced profile; not an experimentally validated performance claim.

Known limitations

  • Complete dependency commercial rights and independently validated binding performance have not yet been verified.

Technical limitations are included only when supported by documented sources.

Commercial licensing

Commercial permission — Unverified

Official code repository uses MIT and Hugging Face metadata labels the model MIT, but all checkpoint, underlying ProGen2, evaluation and dependency commercial terms have not been independently established. Do not infer complete commercial clearance.

License fee — Unverified

Public code and model files are downloadable; no verified all-in commercial cost. GPU, hosting, dependencies and any separately licensed components may incur costs.

Free downloads do not necessarily permit company use. Code, checkpoints, external dependencies and compute expenses require separate review.

Official references

Validate your designed binder.

Seq2Study connects AI-designed proteins and antibodies with expression, affinity, stability and developability testing.

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