IgLM
Antibody-specific generative language model - academic licence only.
Developer: Gray Lab, Johns Hopkins University
Overview
- Developer
- Gray Lab, Johns Hopkins University
- Category
- Protein language models
- Commercial rights
- Non-commercial
- Commercial cost
- No commercial option
- Compute
- Single GPU
- Open weights
- Yes
- Last verified
Capabilities
Generates and infills antibody sequences conditioned on species and chain type. Input: a partial antibody sequence with a span to fill, plus species/chain tokens; output: completed sequences with likelihoods, used for library generation and for scoring how natural a designed CDR looks.
When to use it
Academic antibody library generation and naturalness scoring. For commercial work, AbLang2 (BSD-3) and IgBert/IgT5 (MIT) cover the same ground.
Input / Output
- Input
- a partial antibody sequence with a span to fill, plus species/chain tokens
- Output
- completed sequences with likelihoods, used for library generation and for scoring how natural a designed CDR looks
Compute
Single GPU. Other tools with this compute profile →
Commercial Licensing
Commercial rights — may a company use it?
Not for commercial useLicence as writtenJHU Academic Software License Agreement
LICENSE.md is the JHU Academic Software License Agreement, effective only between JHU and 'a non-profit academic or non-profit research institution'. Same pattern as IgFold from the same lab. A company needs a separate agreement with JHU.
The licence limits use to non-commercial purposes; a company needs a separate agreement.
Commercial cost — is commercial use free of charge?
No commercial option at any priceNo fee for academics; no published commercial price. Commercial use would require negotiating with JHU's technology transfer office.
Price and rights are separate: this panel is about money, the panel above is about permission.
- Commercial OK ≠ Free of charge. A tool can be licensed for company use and still need a paid licence for a dependency (BindCraft → PyRosetta).
- Free download ≠ Commercially licensed. Weights you can download at no cost may still forbid commercial use (AlphaFold 3).
- Unverified ≠ Commercially permitted. If no published statement settles it, treat it as unknown — not as a yes.
- Every component counts. Each status considers the code licence, the model-weights terms, required dependencies and any terms of use.
Model Weights
Open weights. A separate weights licence is Not documented as its own field; where weights carry different terms from the code, that is stated in the licence explanation above.
Dependencies
Not documented as a separate field. Any dependency that affects commercial use (for example a paid PyRosetta licence) is named in the licence and cost explanations above.
Official References
- Official site / repo
- github.com/Graylab/IgLM
- Licence sources
From the makers of FoldScout
From AI Design to Wet-Lab Validation
Designed a promising protein or antibody? Seq2Study helps translate AI-generated sequences into experimental data.
- Protein Expression
- Protein Purification
- Binding Affinity
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