TAP (Therapeutic Antibody Profiler)
Flags antibody developability risks against clinical-stage antibody ranges.
Developer: OPIG, University of Oxford (SAbPred web server)
Overview
- Developer
- OPIG, University of Oxford (SAbPred web server)
- Commercial rights
- Unverified
- Commercial cost
- Cost unverified
- Compute
- Hosted service
- Open weights
- Unverified
- Last verified
Capabilities
Developability red flags. Input: an antibody Fv structure (or sequence to be modelled); output: five TAP metrics - CDR length, patches of surface hydrophobicity, positive and negative charge, and charge asymmetry - each placed against the distribution of clinical-stage antibodies.
When to use it
Quick red-flag check (CDR length, patch hydrophobicity, charge) on a handful of candidates. It is a comparison against clinical-stage distributions, not a measurement, and the web server is rate-limited for bulk work.
Input / Output
- Input
- an antibody Fv structure (or sequence to be modelled)
- Output
- five TAP metrics - CDR length, patches of surface hydrophobicity, positive and negative charge, and charge asymmetry - each placed against the distribution of clinical-stage antibodies
Compute
Hosted service. Other tools with this compute profile →
Commercial Licensing
Commercial rights — may a company use it?
UnverifiedLicence as writtenunverified
The SAbPred TAP web page states no license or terms of use, and no public source repository license was found; terms for commercial use are therefore unverified.
We could not find a published statement that settles it (often: the model weights carry no licence). Treat as unknown.
Commercial cost — is commercial use free of charge?
Cost unverifiedThe TAP web server is offered for free use through OPIG, but no licence or terms page was found that states whether a company may use it, so neither the right nor any commercial fee is settled. Treat as unknown.
Price and rights are separate: this panel is about money, the panel above is about permission.
- Commercial OK ≠ Free of charge. A tool can be licensed for company use and still need a paid licence for a dependency (BindCraft → PyRosetta).
- Free download ≠ Commercially licensed. Weights you can download at no cost may still forbid commercial use (AlphaFold 3).
- Unverified ≠ Commercially permitted. If no published statement settles it, treat it as unknown — not as a yes.
- Every component counts. Each status considers the code licence, the model-weights terms, required dependencies and any terms of use.
Model Weights
Weights: unverified. A separate weights licence is Not documented as its own field; where weights carry different terms from the code, that is stated in the licence explanation above.
Dependencies
Not documented as a separate field. Any dependency that affects commercial use (for example a paid PyRosetta licence) is named in the licence and cost explanations above.
Official References
- Official site / repo
- opig.stats.ox.ac.uk/webapps/sabdab-sabpred/sabpred/tap
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